{"id":9816,"date":"2019-01-22T14:13:46","date_gmt":"2019-01-22T13:13:46","guid":{"rendered":"https:\/\/udic.es\/%e2%80%8blhospital-general-de-catalunya-participa-en-estudi-per-frenar-la-progressio-del-parkinson\/"},"modified":"2019-01-24T10:02:32","modified_gmt":"2019-01-24T09:02:32","slug":"%e2%80%8blhospital-general-de-catalunya-participa-en-estudi-per-frenar-la-progressio-del-parkinson","status":"publish","type":"post","link":"https:\/\/udic.es\/ca\/%e2%80%8blhospital-general-de-catalunya-participa-en-estudi-per-frenar-la-progressio-del-parkinson\/","title":{"rendered":"\u200bL’Hospital General de Catalunya participa en estudi per frenar la progressi\u00f3 del Parkinson"},"content":{"rendered":"
\n
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Actualment hi ha dos projectes d’investigaci\u00f3 sobre aquest tipus de f\u00e0rmacs<\/h2>\n<\/div>\n<\/div>\n
\n
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13 de juny de 2018 a les 15:38 |<\/p>\n

L’Hospital General de Catalunya. | ACN
\nAquesta informaci\u00f3 es va publicar originalment el 13 de juny de 2018 i, per tant, la informaci\u00f3 que hi apareix fa refer\u00e8ncia a la data especificada.
\nL’Hospital Universitari General de Catalunya, a Sant Cugat del Vall\u00e8s, s’afegeix com a participant a un estudi per frenar la progressi\u00f3 de la malaltia del Parkinson. Segons informa el centre, el doctor Ernest Balaguer, neur\u00f2leg, director de Recerca de l’Hospital i investigador principal, participa en un assaig cl\u00ednic disruptiu amb un tractament farmacol\u00f2gic de nova generaci\u00f3 que pret\u00e9n bloquejar o suprimir una prote\u00efna associada a la malaltia del Parkinson i aix\u00ed poder frenar la seva progressi\u00f3.<\/p>\n

Es tracta del alfa-sinucle\u00efna, una prote\u00efna an\u00f2mala que es creu que \u00e9s la responsable de l’avan\u00e7 del Parkinson, un trastorn neurodegeneratiu de causa desconeguda, que produeix tremolor de rep\u00f2s, lentitud de moviments i rigidesa, s’origina per un d\u00e8ficit de dopamina a nivell dels ganglis basals i es caracteritz per la pres\u00e8ncia d’aquesta prote\u00efna an\u00f2mala que \u00e9s l’alfa-sinucle\u00efna. En aquest assaig s’ha considerat que el Parkinson es relaciona amb la pres\u00e8ncia del alfasinucle\u00edna i si es pot eliminar o bloquejar la transmissi\u00f3 d’aquesta prote\u00efna, es podria revertir la progressi\u00f3 de la malaltia.<\/p>\n

El tractament pret\u00e9n diluir els dip\u00f2sits d’alfa-sinucle\u00efna els que es creu que s\u00f3n els responsables de l’avan\u00e7 del Parkinson, per la qual cosa amb aquest assaig cl\u00ednic no es pretenen millorar els s\u00edmptomes sin\u00f3 millorar la malaltia i, pot ser, curar-la. L’estudi est\u00e0 dirigit a pacients inicials sense tractament o amb un tractament menor, t\u00e9 una durada de dos anys i es realitzar\u00e0 a uns 300 pacients de tot el m\u00f3n, dels quals un gran nombre ja estan actualment en tractament.<\/p>\n

S’estima que en uns 10 anys a tot el m\u00f3n hi haur\u00e0 uns 15.000.000 de persones afectades de Parkinson, de manera que a l’Hospital Universitari General de Catalunya es desenvolupen diverses l\u00ednies d’investigaci\u00f3 a trav\u00e9s de la UIC (Unitat d’Investigaci\u00f3 Cl\u00ednica), liderada pel Dr. Ernest Balaguer. Actualment hi ha dos projectes d’investigaci\u00f3 sobre aquest tipus de f\u00e0rmacs. Un d’ells \u00e9s aquest que ha comen\u00e7at ara i l’altre est\u00e0 previst que comenci despr\u00e9s de l’estiu, els dos de f\u00e0rmacs d’anticossos monoclonals antialfa-sinucle\u00efna.<\/p>\n

Del que est\u00e0 en marxa ja s’han reclutat pacients en el nostre centre, i est\u00e0 en fase d’experimentaci\u00f3, i cal destacar que, dels \u00faltims set medicaments anti-Parkinson que han sortit al mercat a Espanya, tots ells havien estat avaluats en l’Hospital General, ja que t\u00e9 una gran experi\u00e8ncia en aquests f\u00e0rmacs. A m\u00e9s, tamb\u00e9 s’estan realitzant importants estudis amb nous f\u00e0rmacs en malaltia d’Alzheimer, patologia vascular cerebral, epil\u00e8psia i altres patologies.<\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Actualment hi ha dos projectes d’investigaci\u00f3 sobre aquest tipus de f\u00e0rmacs 13 de juny de 2018 a les 15:38 | L’Hospital General de Catalunya. | ACN Aquesta informaci\u00f3 es va publicar originalment el 13 de juny de 2018 i, per tant, la informaci\u00f3 que hi apareix fa refer\u00e8ncia a la data especificada. L’Hospital Universitari General…<\/p>\n","protected":false},"author":2,"featured_media":9779,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[125],"tags":[],"class_list":["post-9816","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-parkinson-ca"],"yoast_head":"\n\u200bL'Hospital General de Catalunya participa en estudi per frenar la progressi\u00f3 del Parkinson - UDIC Unitat D'Investigaci\u00f3 Cl\u00ednica<\/title>\n<meta name=\"description\" content=\"Actualment hi ha dos projectes d'investigaci\u00f3 sobre aquest tipus de f\u00e0rmacs 13 de juny de 2018 a les 15:38 | L'Hospital General de Catalunya. | ACN\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/udic.es\/ca\/\u200blhospital-general-de-catalunya-participa-en-estudi-per-frenar-la-progressio-del-parkinson\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u200bL'Hospital General de Catalunya participa en estudi per frenar la progressi\u00f3 del Parkinson - 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